Metabolic disturbances, including oxidative stress, mitochondrial dysfunction, and DNA damage, accelerate senescence, impair cellular repair mechanisms, and drive the progression of age-related diseases. Additionally, stem cells, which are essential for tissue maintenance and regeneration, experience age-related decline due to metabolic shifts, reducing their ability to repair damage and contributing to both degenerative conditions and malignancies.

During this meeting, we will explore the intricate connections between metabolism, senescence, mitochondria, DNA stability, stem cell biology, cancer, and age-related diseases. By bringing together leading experts, this symposium aims to advance discussions on the latest strategies to modulate aging, enhance tissue regeneration, and develop innovative therapies to combat age-related diseases and cancer, ultimately promoting healthier aging and longevity.